The Sculptique Aesthetics
Retatrutide: The Triple-Action Weight-Loss Drug Changing the Game
What is retatrutide? How it differs from Ozempic and Mounjaro—triple GLP-1/GIP/glucagon agonist, weight loss potential, and what to expect. The Sculptique Aesthetics, Mumbai.

Retatrutide is an emerging weight-loss medication that targets three hormone pathways—GLP-1, GIP, and glucagon—unlike Ozempic (semaglutide) or Mounjaro (tirzepatide), which target one or two. Early trials suggest retatrutide may produce significant weight loss, but it is not yet widely approved for obesity. If you're researching weight loss drugs, Ozempic alternatives, or retatrutide availability in Mumbai or India, this guide explains what retatrutide is, how it works, and how it compares. The Sculptique Aesthetics serves Mumbai, Bandra, Khar, Andheri, South Mumbai, and India with evidence-based information on weight loss and body contouring options.

What is retatrutide?
Retatrutide is a triple agonist—it activates GLP-1, GIP, and glucagon receptors. GLP-1 and GIP help reduce appetite and improve blood sugar; glucagon may further support metabolism and fat loss. Ozempic (semaglutide) is a GLP-1 agonist; Mounjaro (tirzepatide) is GLP-1 + GIP. Retatrutide adds glucagon, which could mean greater weight loss in studies—but also more to learn about safety and long-term use. Weight loss drugs are not a substitute for healthy diet and exercise; they are tools that work best with lifestyle change.
Retatrutide vs Ozempic vs Mounjaro
| Ozempic (semaglutide) | Mounjaro (tirzepatide) | Retatrutide | |
|---|---|---|---|
| Mechanism | GLP-1 | GLP-1 + GIP | GLP-1 + GIP + glucagon |
| Approval | Diabetes; weight (Wegovy) | Diabetes; weight (Zepbound) | In trials |
| Weight loss (trials) | Significant | Often greater than Ozempic | Early data very strong |
Retatrutide is still in clinical trials for obesity; availability in India and Mumbai may follow regulatory approval. Ozempic for weight loss Mumbai and Mounjaro are more established options today. See retatrutide vs Ozempic for a deeper comparison.
Who might consider retatrutide?
When retatrutide becomes available, it may be considered for obesity or overweight with related health risks—similar to Ozempic and Mounjaro. Weight loss drugs are not for everyone; they require medical supervision. Retatrutide side effects may include nausea, constipation, and GI issues, as with other GLP-1-based drugs. Weight loss in Mumbai and India should be guided by a doctor who can assess eligibility and monitor you.
Weight loss and body contouring
Rapid weight loss from Ozempic, Mounjaro, or (in future) retatrutide can leave loose skin or stubborn fat. Body contouring—including liposuction, tummy tuck, or post–weight loss body contouring—can address what diet and drugs cannot. The Sculptique Aesthetics offers body contouring Mumbai for patients who have lost weight and want to refine their shape.
Conclusion
Retatrutide is a triple-action weight-loss drug that could change the game once approved and available. For now, Ozempic and Mounjaro remain the main GLP-1 options in many regions. If you're exploring weight loss drugs or body contouring after weight loss, contact us at The Sculptique Aesthetics for a consultation. Serving Mumbai, Bandra, Khar, Andheri, South Mumbai, and India.







